Human Vaginal Epithelium

DESCRIPTION
The vaginal epithelium is the mucous membrane found in the internal cell layers of the vagina. It is made of non-keratinized squamous epithelium on a dense chorion with elastic fibers.

After 5 days of tissue culture of in defined cell culture medium, vaginal epithelum model demonstrating all the characteristics of the in vivo vaginal mucosa.

The vaginal epithelium model is characterized by a barrier function and metabolic activity and can be employed for safety and efficacy testing. To ensure global availability, models are transported on an agarose based solidified medium together with Sterlab growth and maintenance medium.

RECOMMENDED MEDIUM
Growth Medium (Ref: 205MILC – 125ml, 250ml or 500ml).

PRODUCT CHARACTERIZATION
Each production batch is provided with quality controls values and recommendations such as storage conditions, instruction for use, batch number and origin, histology, cell viability, absence of Hepatitis B, Hepatitis C, HIV, and Mycoplasma.

PRODUCT USE
The Sterlab RHV model are for in vitro research use only and not for diagnostic or clinical applications.

APPLICATION
The Vaginal epithelium model can be employed to test the safety and efficacy of chemicals, cosmetics, and pharmaceutical compounds. Due to a dry surface, the vaginal epithelium model allows realistic topical application scenarios for a broad range of liquid and solid substances. Moreover, a systemic application can be simulated by applying test substances into the culture medium.