Human Full Thickness

DESCRIPTION

The Full Thickness model is an in vitro 3D model constituted of 2 main tissues: an epidermis developed on a dermal equivalent using a chemically defined medium.

The epidermis is derived from normal primary human keratinocytes isolated from neonatal skin. The dermal equivalent consist of a mixture of collagen I and primary human fibroblasts.

After 10 days of tissue culture, the Full Thickness model presents a stratified and well differentiated epidermis likely to the in vivo skin.

Ki67 staining

E-caderine staining

RECOMMENDED MEDIUM
Growth Medium (Ref: 205MILC – 125ml, 250ml or 500ml).

PRODUCT CHARACTERIZATION
Each production batch is provided with quality controls values and recommendations such as storage conditions, full thickness instruction for use, batch number and origin, histology, cell viability, barrier function integrity, absence of Hepatitis B, Hepatitis C, HIV, and Mycoplasma.

PRODUCT USE
The Sterlab Full Thickness model are for in vitro research use only and not for diagnostic or clinical applications.